The Arizona Cardinals are set to host the Seattle Seahawks in a promising regular season encounter at State Farm Stadium on September 20, 2026. The game kicks off at 4:25 pm, marking a pivotal moment early in the season for both teams.

As the home team, the Arizona Cardinals will look to leverage their home-field advantage against the Seahawks. This game offers the Cardinals an excellent opportunity to set the tone for their season, playing in front of their passionate fans in Glendale.

The Seattle Seahawks, on the other hand, will surely come prepared to challenge the Cardinals. This matchup is crucial as both teams vie for early momentum, seeking to establish a tempo for the upcoming games. It’s a game that could highlight strategic nuances and reveal potential strengths and weaknesses in both squads.

Betting lines: Arizona Cardinals 4.50, Seattle Seahawks -4.50. Total: 41.50. Moneyline: Arizona Cardinals 185, Seattle Seahawks -225. (DraftKings)

Stay tuned to betArizonasports.com for more insights and updates on this game and other sporting events.